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From M1....
When switching to Mobil 1 in higher mileage vehicles, we recommend an initial short (2,000 to 3,000 miles) oil change, both oil and filter. This will allow Mobil 1 to clean some of the engine deposits that have accumulated over time. Following this initial short oil change, continue with your normal oil change interval.
You should be fine switching to synthetic, I have done so on several cars with over 100,000 miles with no problems (in one I even had lower oil consumption). The reason that you hear that you shouldn't switch on high mile cars comes from the original Mobil 1 back in the 80's when they didn't put a seal sweller in the oil. With older cars that had marginal seals the extra cleaning in the Mobil would flush all the gunk out and they would leak like mad. Once mobile started to put the seal swell in, the problem went away.
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