As long as you can increase VE more than you increase parasitic power loss, you should do okay.
Still, I can't understand why anyone would comprimise the inherent simplicity of a turbosupercharger by piggy-backing a heavy electric motor onto it with the attendant wiring complexity issues.
If instant boost is the goal without using nitrous or a mechanical supercharger, look WAY out of the box. As all things, balanced comprimise is the driver and, in my opinion, this aint the way to get it. Low-rpm nitrous seems the best to me.
Of course, this could just be an amusing engineering exercise, like solar-powered racers. Precisely stated goal, precisely stated techologies to use, totally unusable as a replacement passenger vehicle for use by the masses. There will be some useful automotive technology that trickles out of the program but I think it's headed the wrong direction.